HOW ANACETRAPIB INHIBITS THE ACTIVITY OF THE CHOLESTERYL ESTER TRANSFER PROTEIN? PERSPECTIVE THROUGH ATOMISTIC SIMULATIONS.

How anacetrapib inhibits the activity of the cholesteryl ester transfer protein? Perspective through atomistic simulations.

Cholesteryl ester transfer protein (CETP) mediates the reciprocal transfer of neutral lipids (cholesteryl esters, triglycerides) and phospholipids between different lipoprotein fractions in human blood plasma.A novel molecular agent known as anacetrapib has been shown to inhibit CETP activity and thereby raise high density lipoprotein (HDL)-cholest

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Toroidal and elliptic quiver BPS algebras and beyond

Abstract The quiver Yangian, an infinite-dimensional algebra introduced recently in [1], is the Handheld Games algebra underlying BPS state counting problems for toric Calabi-Yau three-folds.We introduce trigonometric and elliptic analogues of quiver Yangians, which we call toroidal quiver algebras and elliptic quiver algebras, respectively.We cons

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In-vitro and in-vivo evaluation of different fungicides against leaf blight causing fungus Alternaria cucumerina in bitter gourd

Bitter gourd (Momordica charantia L.) belongs to family Cucurbitaceae, and is a popular vegetable crop in the tropical and sub-tropical countries.It is an annually grown herbaceous vine that requires warm climate for growth.The leaves, stem and roots of bitter gourd contains a lot of bio-active components having nutritional and medicinal importance

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